is it better to use 2 or 4 ram slots

For Dual Channel technology to work, the RAM sticks must be plugged into the correct slots. ... If you have two RAM slots, it doesn’t matter which slot you use for your RAM, but if you have four or more, it does matter.

If your motherboard supports 16 GB of RAM and has 4 slots (dual-channel), you can install four 4 GB sticks or two 8 GB sticks to reach the limit. Use a ...

Does It Matter Which RAM Slot You Use? ... Which RAM Slot to Use for a Single Stick?